During which semester is a client most likely to develop gestational diabetes?

Gestational diabetes is most commonly diagnosed in the third trimester of pregnancy. During this period, the body undergoes significant hormonal changes, which can affect insulin sensitivity. As the placenta grows, it produces higher levels of hormones such as human placental lactogen and corticotropin-releasing hormone, which can lead to increased insulin resistance. This means the body may not be able to produce enough insulin to maintain normal blood glucose levels, resulting in gestational diabetes.

The likelihood of developing gestational diabetes increases with gestational age, particularly in the later part of the pregnancy, which is why it is typically screened for in the third trimester. While some women may experience risk factors earlier in the pregnancy, routine screening and diagnosis usually take place between the 24th and 28th weeks, firmly placing the peak risk in the third trimester.