What critical assessment is made when a patient is on tizanidine?

When a patient is on tizanidine, monitoring hepatic function is critical because the medication is primarily metabolized by the liver. Tizanidine can lead to hepatotoxicity, which can manifest as elevated liver enzymes and potential liver damage. Regular assessment of liver function tests (LFTs) is essential to ensure that the patient does not develop significant liver issues while on this medication.

In cases of liver impairment, the dosing of tizanidine may need to be adjusted to prevent further complications. Therefore, assessing hepatic function ensures the safe and effective use of tizanidine in managing muscle spasticity.