What is a risk associated with the use of valproic acid?

Valproic acid, also known as valproate, is an anticonvulsant medication commonly used to treat epilepsy, bipolar disorder, and to prevent migraines. One of the significant risks associated with the use of valproic acid is liver damage. This risk is particularly concerning because valproic acid can lead to hepatotoxicity, especially in certain populations such as young children and individuals with pre-existing liver conditions. The potential for liver damage necessitates monitoring of liver function tests before and periodically during treatment to detect any signs of hepatic impairment early. Understanding this risk is crucial for healthcare providers in managing therapy with valproic acid effectively and safeguarding patients from serious complications associated with liver damage.