When administering cyclophosphamide to a child with neuroblastoma, what important action should the nurse take?

Maintaining hydration with liberal fluid intake is critical when administering cyclophosphamide, especially in pediatric patients with neuroblastoma. Cyclophosphamide is known to have potential nephrotoxic effects and can lead to hemorrhagic cystitis. Encouraging high fluid intake helps to dilute the urine and facilitates renal clearance of the drug, reducing the risk of bladder irritation and other complications. By promoting hydration, the nurse can help ensure that the child remains safe and minimize the side effects associated with the chemotherapy treatment.

Incorporating this hydration strategy is a best practice when dealing with chemotherapeutic agents that can affect the urinary system, making it an essential part of the administration process for such medications.