Which factor increases the risk of developing osteoporosis?

Estrogen deficiency is a significant risk factor for developing osteoporosis, particularly in postmenopausal women. Estrogen plays a crucial role in regulating bone metabolism by inhibiting bone resorption (the process where bone is broken down) and promoting bone formation. When estrogen levels drop, as they do during menopause, there is an increase in bone resorption and a subsequent loss of bone density, leading to a higher risk of osteoporosis. This condition can result in weakened bones and an increased likelihood of fractures.

In contrast, high calcium intake, regular exercise, and good hydration are all factors that are generally associated with bone health and may help to prevent osteoporosis rather than increase its risk. High calcium intake provides the necessary nutrients for bone strength, regular exercise, particularly weight-bearing activities, helps maintain bone density, and good hydration supports overall bodily functions, including those related to bone health. Thus, the absence of sufficient estrogen is a clear and compelling reason for increased susceptibility to this disease.