Which initial action should a nurse take when a client shows signs of anaphylaxis after IV medication administration?

In a situation where a client displays signs of anaphylaxis following IV medication administration, the most immediate and appropriate initial action is to stop the infusion of the medication. Anaphylaxis is a severe, life-threatening allergic reaction that can rapidly progress, and stopping the infusion removes the trigger that is likely causing the reaction to escalate.

Following the cessation of the medication, the nurse can then proceed to administer epinephrine and implement other emergency interventions. It is crucial to act promptly in such situations to minimize the patient's exposure to the allergen and stabilize their condition. After stopping the infusion, calling for assistance or providing oxygen may be necessary steps, but they come after the critical action of stopping the infusion to prevent further harm.