Which of the following symptoms would indicate a need for monitoring in clients receiving tobramycin?

Rising blood urea nitrogen (BUN) levels are indicative of renal function impairment, which is a critical consideration when monitoring clients receiving tobramycin. Tobramycin is an aminoglycoside antibiotic known for its potential nephrotoxic effects. Increased levels of BUN suggest that the kidneys are not filtering waste properly, signaling that the drug may be affecting renal function.

Monitoring BUN levels is essential for early detection of kidney damage, enabling timely intervention to prevent further complications. This consideration is particularly important as aminoglycosides can accumulate in the body, leading to toxicity, especially in clients with preexisting renal impairment or those on concurrent nephrotoxic medications.

Maintaining vigilance regarding BUN and overall renal function in patients treated with tobramycin helps ensure patient safety and optimal therapeutic outcomes.